Ageratum houstonianum Extract and Agerarin Promote Hair Growth via MAPK/AP-1 Axis-Dependent Upregulation of SCUBE3 in Human Dermal Papilla Cells
gene promoter activity. AHE and agerarin promoted hair follicle growth by upregulating SCUBE3 expression via activation of the MAPK-AP-1 signaling axis. In conclusion, AHE and agerarin may serve as potential therapeutic agents for the prevention and treatment of alopecia (hair loss).
Authors
- Euitaek Jung (ORCID: https://orcid.org/0000-0003-3091-0649)
- Soon Young Shin (ORCID: https://orcid.org/0000-0002-1075-0011)
- Yena Choi
- Yongjin Kim
Institutions
- Konkuk University (KR)
- Skin Research Center (FR)
Publication Details
- Journal
- International Journal of Molecular Sciences
- Published
- 2026-04-20
- DOI
- https://doi.org/10.3390/ijms27083679
- Primary Topic
- Hair Growth and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Konkuk University