Design, Synthesis and Biological Evaluation of 6H-Benzimidazo[1′,2′:1,2]pyrido[3,4- <i>b</i> ]indole Derivatives as TDP1 Inhibitors: Potent Synergistic Agents with Topotecan against Cervical Cancer
Authors
Hao Yang (ORCID: https://orcid.org/0000-0001-5351-1806)
Zeyong Huang
Nan Wang (ORCID: https://orcid.org/0000-0002-0983-3389)
Yuanbei Zhuang
Hua Nie (ORCID: https://orcid.org/0000-0003-3197-7917)
Jiunlong Yang
Lingfeng Wu
Jiayao Liu
Hui Huang
Yuman Xie
Xuerou Zheng
Shengyuan Zhang
Bo Qiu
Institutions
Sun Yat-sen University (CN)
Jiaying University (CN)
Ningxia Medical University (CN)
Third Affiliated Hospital of Sun Yat-sen University (CN)
Traditional Chinese Medicine Bureau of Guangdong Province
Science and Technology Planning Project of Guangdong Province
Basic and Applied Basic Research Foundation of Guangdong Province
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article
Design, Synthesis and Biological Evaluation of 6H-Benzimidazo[1′,2′:1,2]pyrido[3,4- b ]indole Derivatives as TDP1 Inhibitors: Potent Synergistic Agents with Topotecan against Cervical Cancer
Hao Yang, Zeyong Huang, Nan Wang, Yuanbei Zhuang et al.
Journal
Journal of Medicinal Chemistry
Topics
Cancer therapeutics and mechanisms
article
Design, Synthesis and Biological Evaluation of 6H-Benzimidazo[1′,2′:1,2]pyrido[3,4- b ]indole Derivatives as TDP1 Inhibitors: Potent Synergistic Agents with Topotecan against Cervical Cancer
Hao Yang, Zeyong Huang, Nan Wang, Yuanbei Zhuang, Hua Nie, Jiunlong Yang, Lingfeng Wu, Jiayao Liu, Hui Huang, Yuman Xie, Xuerou Zheng, Shengyuan Zhang, Bo Qiu
article en
Abstract
No abstract available for this paper.
Publication Tag
Journal of Medicinal Chemistry
Institutions
Sun Yat-sen University (CN), Jiaying University (CN), Ningxia Medical University (CN), Third Affiliated Hospital of Sun Yat-sen University (CN)
Funders
Department of Education of Guangdong Province, Traditional Chinese Medicine Bureau of Guangdong Province, Science and Technology Planning Project of Guangdong Province, Basic and Applied Basic Research Foundation of Guangdong Province