Comprehensive approaches to combat AMR empower discovery research efforts

Comprehensive approaches to combat AMR empower discovery research efforts Antonio Ruzzini shares how enduring efforts to uncover AMR determinants in agrifood will enhance our understanding and management of the ongoing AMR crisis. The World Organisation for Animal Health (WOAH) and its List of Antimicrobial Agents of Veterinary Importance remind us that we possess a finite number of antibiotics to combat bacterial infections. The antimicrobial resistance (AMR) crisis is defined by the emergence of pathogens with genetic determinants that protect them from these essential therapies. Thousands of genetic determinants are known. How many AMR genes (ARGs) we have left to discover, what might evolve, and what might become prominent are unknowns.