A sellar mass as the initial presentation of pituitary infiltration by diffuse large B-cell lymphoma: a case report

Systemic lymphoma involving the pituitary region is rare and often presents with nonspecific symptoms, making diagnosis challenging. This work reports a case of diffuse large B-cell lymphoma (DLBCL) involving the pituitary gland that initially appeared as a sellar mass. The clinical presentation, diagnostic workup (including biochemical and imaging findings), and management of this condition were discussed.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-04-21
DOI
https://doi.org/10.3389/fonc.2026.1686394
Primary Topic
CNS Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

A sellar mass as the initial presentation of pituitary infiltration by diffuse large B-cell lymphoma: a case report

Jing Liu, Xiangyu Xu, Hui Chen, Gengxue Jin et al.
Frontiers in Oncology
CNS Lymphoma Diagnosis and Treatment
article

A sellar mass as the initial presentation of pituitary infiltration by diffuse large B-cell lymphoma: a case report

Jing Liu, Xiangyu Xu, Hui Chen, Gengxue Jin, Huitao Meng
article en

Abstract

Systemic lymphoma involving the pituitary region is rare and often presents with nonspecific symptoms, making diagnosis challenging. This work reports a case of diffuse large B-cell lymphoma (DLBCL) involving the pituitary gland that initially appeared as a sellar mass. The clinical presentation, diagnostic workup (including biochemical and imaging findings), and management of this condition were discussed.

Frontiers in OncologyVol. 16
Lanzhou University Second Hospital (CN), Pulmonary Hospital of Lanzhou (CN), Lanzhou University (CN)
Openalex Percentile: Top 18%
CNS Lymphoma Diagnosis and Treatment
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