Anomalous hemorrhage in myxopapillar ependymoma: illustrative case.

BACKGROUND: This is the case of a 22-year old male with bilateral leg pain caused by an intradural lesion at the L3 level. On MRI, there were no signs of hemorrhage. Resection was performed and a raspberry-like lesion with attached veins was identified. Histopathological analysis showed a myxopapillary ependymoma. OBSERVATIONS: Although hemorrhage is rare, myxopapillary ependymomas are highly vascularized and carry the highest risk of intratumoral bleeding among spinal ependymomas. In the literature, most patients with hemorrhage of myxopapillary ependymomas present with neurological deterioration. Rarely are these patients noted to be clinically stable. LESSONS: Despite no worsening of symptoms or preoperative evidence of hemorrhage, intraoperative findings revealed a hemorrhagic lesion attached to vascular structures and potentially the filum terminale. Hemorrhage in a myxopapillary ependymoma without clinical deterioration is a rare occurrence. https://thejns.org/doi/10.3171/CASE25791.

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PubMed
Published
2026-04-20
DOI
https://doi.org/10.3171/case25791
Primary Topic
Glioma Diagnosis and Treatment
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article
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article

Anomalous hemorrhage in myxopapillar ependymoma: illustrative case.

Ferenc A. van Nie, Inge J M H Caelers, Anouk Y J M Smeets
PubMed
Glioma Diagnosis and Treatment
article

Anomalous hemorrhage in myxopapillar ependymoma: illustrative case.

Ferenc A. van Nie, Inge J M H Caelers, Anouk Y J M Smeets
article en

Abstract

BACKGROUND: This is the case of a 22-year old male with bilateral leg pain caused by an intradural lesion at the L3 level. On MRI, there were no signs of hemorrhage. Resection was performed and a raspberry-like lesion with attached veins was identified. Histopathological analysis showed a myxopapillary ependymoma. OBSERVATIONS: Although hemorrhage is rare, myxopapillary ependymomas are highly vascularized and carry the highest risk of intratumoral bleeding among spinal ependymomas. In the literature, most patients with hemorrhage of myxopapillary ependymomas present with neurological deterioration. Rarely are these patients noted to be clinically stable. LESSONS: Despite no worsening of symptoms or preoperative evidence of hemorrhage, intraoperative findings revealed a hemorrhagic lesion attached to vascular structures and potentially the filum terminale. Hemorrhage in a myxopapillary ependymoma without clinical deterioration is a rare occurrence. https://thejns.org/doi/10.3171/CASE25791.

PubMedVol. 11(16)
Maastricht University Medical Centre (NL), Zuyderland Medisch Centrum (NL)
Good health and well-being
Openalex Percentile: Top 11%
Glioma Diagnosis and Treatment
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