Anti-obesity medication use sparks effort-based sanctions and social penalties

Obesity is one of the most widespread public health risks, with more than 1 billion affected individuals worldwide. While treatment with 'anti-obesity' medication (GLP-1 agonists) shows promising results, patients face public backlash for 'cutting corners'. Across four pre-registered within-subject studies in three countries (N = 1.205, Belgium, US, UK), we found that users of GLP-1 medication are perceived as less moral, presumably because they are thought to have exerted less effort in their weight-loss endeavor. Further, we observed effects on broader consequences (e.g., competence or deservingness perceptions) and tested candidate moderators (e.g., attitudes, experience, personality). Our findings highlight the adverse consequences of effort-based biases experienced by patients using anti-obesity medication and underscore the need for public education and stigma reduction.

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Publication Details

Journal
Scientific Reports
Published
2026-04-21
DOI
https://doi.org/10.1038/s41598-026-42166-y
Primary Topic
Pharmacology and Obesity Treatment
Type
article
Field-Weighted Citation Impact
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article

Anti-obesity medication use sparks effort-based sanctions and social penalties

Leopold H. O. Roth, Tassilo T. Tissot
Scientific Reports
Pharmacology and Obesity Treatment
article

Anti-obesity medication use sparks effort-based sanctions and social penalties

Leopold H. O. Roth, Tassilo T. Tissot
article en

Abstract

Obesity is one of the most widespread public health risks, with more than 1 billion affected individuals worldwide. While treatment with 'anti-obesity' medication (GLP-1 agonists) shows promising results, patients face public backlash for 'cutting corners'. Across four pre-registered within-subject studies in three countries (N = 1.205, Belgium, US, UK), we found that users of GLP-1 medication are perceived as less moral, presumably because they are thought to have exerted less effort in their weight-loss endeavor. Further, we observed effects on broader consequences (e.g., competence or deservingness perceptions) and tested candidate moderators (e.g., attitudes, experience, personality). Our findings highlight the adverse consequences of effort-based biases experienced by patients using anti-obesity medication and underscore the need for public education and stigma reduction.

Scientific ReportsVol. 16(1)
Austrian Institute of Economic Research (AT), Ghent University (BE)
Openalex Percentile: Top 21%
Pharmacology and Obesity Treatment
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Anti-obesity medication use sparks effort-based sanctions and social penalties — Leopold H. O. Roth, Tassilo T. Tissot · Scientific Reports (2026) | TGRS Research Map | TGRS