Predictive value of elastography (Shear-Wave and Elasticity Index) in differentiating benign from malignant breast lesions: a retrospective study in Peru

BACKGROUND: Evidence on the usefulness of quantitative elastography in the characterization of breast lesions remains limited in Latin America and scarce in Peru. This study aims to fill a relevant scientific gap by establishing specific cut-off points to optimize diagnostic interpretation and improve accuracy in differentiating benign from malignant lesions. PATIENTS AND METHODS: receiver operating characteristic (ROC) curve analysis. RESULTS: . 43 kPa; p < 0.001). According to the adjusted model, the Breast Imaging Reporting and Data System (BI-RADS) category remained the most relevant radiological predictor, suggesting that elastography values can be considered complementary for more accurate classification. The optimal SWE cut-off value of ≥ 47.5 kPa demonstrated acceptable diagnostic performance, with a sensitivity of 79.6% and specificity of 67.7%, indicating an adequate ability to distinguish between benign and malignant breast lesions. CONCLUSIONS: This study represents one of the first examples of Peruvian evidence contributing scientific information on the application of quantitative elastography in the evaluation of breast lesions.

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Journal
Radiology and Oncology
Published
2026-04-16
DOI
https://doi.org/10.2478/raon-2026-0018
Primary Topic
Ultrasound Imaging and Elastography
Type
article
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article

Predictive value of elastography (Shear-Wave and Elasticity Index) in differentiating benign from malignant breast lesions: a retrospective study in Peru

Nancy Muñoz, Richard Castillo, Luis Taxa, Jorge Ayon et al.
Radiology and Oncology
Ultrasound Imaging and Elastography
article

Predictive value of elastography (Shear-Wave and Elasticity Index) in differentiating benign from malignant breast lesions: a retrospective study in Peru

Nancy Muñoz, Richard Castillo, Luis Taxa, Jorge Ayon, Jorge Aguilar, Diana Díaz-Llontop, Samantha Mendoza, Claudia Quiñones, Gaston (Wilmer) Mendoza
article en

Abstract

BACKGROUND: Evidence on the usefulness of quantitative elastography in the characterization of breast lesions remains limited in Latin America and scarce in Peru. This study aims to fill a relevant scientific gap by establishing specific cut-off points to optimize diagnostic interpretation and improve accuracy in differentiating benign from malignant lesions. PATIENTS AND METHODS: receiver operating characteristic (ROC) curve analysis. RESULTS: . 43 kPa; p < 0.001). According to the adjusted model, the Breast Imaging Reporting and Data System (BI-RADS) category remained the most relevant radiological predictor, suggesting that elastography values can be considered complementary for more accurate classification. The optimal SWE cut-off value of ≥ 47.5 kPa demonstrated acceptable diagnostic performance, with a sensitivity of 79.6% and specificity of 67.7%, indicating an adequate ability to distinguish between benign and malignant breast lesions. CONCLUSIONS: This study represents one of the first examples of Peruvian evidence contributing scientific information on the application of quantitative elastography in the evaluation of breast lesions.

Radiology and Oncology
Universidad de Lima (PE), Universidad de San Martín de Porres (PE)
Openalex Percentile: Top 14%
Ultrasound Imaging and Elastography
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