Post-vaccination serological status predicts protection against heterologous SAT1 foot-and-mouth disease virus challenge in goats

titer of 2.35 was required to protect 75% (95% CI, 50-90%) of experimentally challenged goats. Simulation modeling estimated a parabolic response curve rather a sigmoid shape as is generated from logistic and probit modeling. Post-vaccinal serological monitoring using VNT or SPCE is theoretically possible in goats to determine the proportion of the population at higher risk for clinical FMD. More research is necessary to determine the relationship between vaccine match and serological titer when modeling vaccinal protection from FMD in goats.