Analysis of body composition characteristics in patients with type 1 diabetes mellitus: a case–control study based on a bioelectrical impedance analyzer

Objective: This study aimed to systematically compare differences in body composition between adult patients with type 1 diabetes mellitus (T1DM) and healthy controls using the bioelectrical impedance analysis (BIA) method, to provide an objective basis for clinical nutritional assessment and intervention in T1DM patients. Methods: A total of 57 T1DM patients hospitalized at the First People's Hospital of Yunnan Province between December 2023 and April 2024 were selected as the study group, and 55 healthy adults matched for age, sex, and BMI were recruited as the control group. Body composition indicators, including body fat, fat-free mass, skeletal muscle, visceral fat area, and phase angle (PA), were measured for all subjects using a body composition analyzer, and the skeletal muscle mass index (SMI) was calculated. BIA was used to determine body composition parameters, and statistical analyses were conducted to compare the differences between the two groups. Results: < 0.05). Conclusion: Despite having normal or even low BMI, T1DM patients present a unique body composition profile characterized by "low fat mass, low visceral fat, but relatively high skeletal muscle mass." This suggests that the disease state may influence energy metabolism and body composition.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-04-21
DOI
https://doi.org/10.3389/fmed.2026.1776074
Primary Topic
Body Composition Measurement Techniques
Type
article
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article

Analysis of body composition characteristics in patients with type 1 diabetes mellitus: a case–control study based on a bioelectrical impedance analyzer

Ji‐Gan Wang, Ran Gu, L Zhang, Jiani Zhu et al.
Frontiers in Medicine
Body Composition Measurement Techniques
article

Analysis of body composition characteristics in patients with type 1 diabetes mellitus: a case–control study based on a bioelectrical impedance analyzer

Ji‐Gan Wang, Ran Gu, L Zhang, Jiani Zhu, Xiaoyun Xi, Tongfen Cui, Luying Yang, Guang Yu, Fan Yang
article en

Abstract

Objective: This study aimed to systematically compare differences in body composition between adult patients with type 1 diabetes mellitus (T1DM) and healthy controls using the bioelectrical impedance analysis (BIA) method, to provide an objective basis for clinical nutritional assessment and intervention in T1DM patients. Methods: A total of 57 T1DM patients hospitalized at the First People's Hospital of Yunnan Province between December 2023 and April 2024 were selected as the study group, and 55 healthy adults matched for age, sex, and BMI were recruited as the control group. Body composition indicators, including body fat, fat-free mass, skeletal muscle, visceral fat area, and phase angle (PA), were measured for all subjects using a body composition analyzer, and the skeletal muscle mass index (SMI) was calculated. BIA was used to determine body composition parameters, and statistical analyses were conducted to compare the differences between the two groups. Results: < 0.05). Conclusion: Despite having normal or even low BMI, T1DM patients present a unique body composition profile characterized by "low fat mass, low visceral fat, but relatively high skeletal muscle mass." This suggests that the disease state may influence energy metabolism and body composition.

Frontiers in MedicineVol. 13
First People's Hospital of Yunnan Province (CN), Guangxi Maternal and Child Health Hospital (CN), County Hospital (GB), Baoshan University (CN), Buffalo General Medical Center (US), Jingning County People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 19%
Body Composition Measurement Techniques
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