Advancing chloramphenicol detection through a novel porous organic polymer-enhanced screen-printed electrode
, a limit of detection of 1.67 μM, and a limit of quantification of 5 μM, along with good repeatability, selectivity, and operational stability over 30 days. Method validation was carried out using pharmaceutical products (topical suspensions, topical gels, injectable suspension, and eye drops) and animal biological samples (cow milk, cow urine and pig urine) containing CAP, yielding satisfactory analytical performance despite the complexity of the matrices and confirming the applicability of the proposed platform for real-sample analysis. These results demonstrate the potential of POPs as effective electrode modifiers for electrochemical sensors.
Authors
- Niculina D. Hădade (ORCID: https://orcid.org/0000-0001-5882-5759)
- Mihaela Tertiş
- Mihaela M. Trandafir (ORCID: https://orcid.org/0000-0001-9001-8738)
- Florentina Neațu (ORCID: https://orcid.org/0000-0002-7885-436X)
- Cécilia Cristea (ORCID: https://orcid.org/0000-0002-4158-3324)
- Cătălin C. Anghel (ORCID: https://orcid.org/0000-0001-5540-4158)
- Mihaela Florea (ORCID: https://orcid.org/0000-0002-6612-6090)
- Ede Bodoki (ORCID: https://orcid.org/0000-0003-4667-2286)
- Maria Suciu (ORCID: https://orcid.org/0000-0001-5449-9108)
- Daniel-Florin Bogoșel (ORCID: https://orcid.org/0009-0005-5991-7379)
- Alexandra Pop
- Ion Grosu
- Iuliana M. Chirica
- Anamaria Blaga Petrean
- Paul C. Martian (ORCID: https://orcid.org/0009-0009-2332-3156)
Institutions
- Iuliu Hațieganu University of Medicine and Pharmacy (RO)
- University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca (RO)
- Babeș-Bolyai University (RO)
- National Institute of Materials Physics (RO)
- National Institute for Research and Development of Isotopic and Molecular Technologies (RO)
Publication Details
- Journal
- Talanta
- Published
- 2026-04-20
- DOI
- https://doi.org/10.1016/j.talanta.2026.129873
- Primary Topic
- Electrochemical sensors and biosensors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii