Prospective Multicenter Evaluation of a multiplex PCR Pneumonia Panel to Distinguish Infectious Pneumonia from Non-Infectious Mimics in ICU Respiratory Failure
CFU/mL.ConclusionsIn ICU patients with suspected pneumonia, a combined negative FAPN and sputum culture result should prompt evaluation for non-infectious mimics. Negative FAPN findings may help reduce unnecessary antibiotic escalation, although their positive predictive value for culture-confirmed bacterial infection is limited.
Authors
- Philip Koon Ngai Lam
- Lap Tin Ho
- Chin Wing Yu
- Viola Chi Ying Chow
- Kwok Ming HO
- Eddie Chi Man Leung (ORCID: https://orcid.org/0000-0002-5036-1707)
- Man Ting Yuk
- Ingrid Yu Ying Cheung
- Duncan Ka Hing Lam (ORCID: https://orcid.org/0009-0006-3025-5196)
- Thomas Yuk Bun Lau
- Alfred Lok Hang Lee (ORCID: https://orcid.org/0000-0002-2161-1420)
Institutions
- Chinese University of Hong Kong (HK)
- Alice Ho Miu Ling Nethersole Hospital (CN)
- York District Hospital (US)
Publication Details
- Journal
- Journal of Intensive Care Medicine
- Published
- 2026-04-20
- DOI
- https://doi.org/10.1177/08850666261442190
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00