Association between the nutritional risk index and postmenopausal osteoporosis in patients with type 2 diabetes mellitus

Objective: To investigate the association between the Geriatric Nutritional Risk Index (GNRI) and the presence of postmenopausal osteoporosis (PMOP) in elderly female patients with type 2 diabetes mellitus (T2DM), and to evaluate the discriminatory ability of GNRI for PMOP in this population. Methods: = 183) based on lumbar spine bone mineral density (BMD) measured by dual-energy X-ray absorptiometry. Data on age, body mass index (BMI), BMD, serological indicators, and GNRI were collected and compared between the two groups. Correlation analysis was performed to examine the relationship between GNRI and various parameters. Binary logistic regression was used to identify independent factors influencing PMOP. The predictive efficacy of GNRI was assessed using the receiver operating characteristic (ROC) curve. Results: < 0.001). The optimal cut-off value was 101.2, with a sensitivity of 70.2% and a specificity of 73.8%. Conclusion: In postmenopausal female patients with T2DM, a higher GNRI value is independently associated with a lower risk of PMOP. GNRI demonstrates moderate discriminatory ability for identifying PMOP in this population and may serve as a simple and useful auxiliary indicator for assessing skeletal health risk in clinical practice, pending further prospective validation.