Deconstructive Alkynylation of Spiro‐Dihydroquinazolinones via Aromatization‐Driven Ring Opening Under Visible Light Irradiation

Here, we report a visible light‐driven, metal‐free photoredox strategy enabling the deconstructive C(sp 3 )–C(sp) coupling of spiro‐dihydroquinazolinones with alkynyl sulfones, providing efficient access to structurally diverse alkynylated quinazolinone scaffolds via an aromatization‐induced radical pathway under mild conditions. Furthermore, translation of the batch protocol to a PFA‐based continuous‐flow reactor enhances reaction efficiency, shortens reaction time, and demonstrates its practical scalability. Mechanistic studies supports the involvement of a radical mediated transformation.