Low-Dose Vitamin C-Based Electroporation of Solid Tumors: A New Area in Non-Cytotoxic Electrochemotherapy

These findings demonstrate that uniform-field reversible electroporation markedly enhances the intracellular delivery and antitumor activity of low-dose vitamin C, supporting this technology-driven strategy as a promising, low-toxicity alternative to conventional chemotherapeutic agents in electrochemotherapy for solid tumors.

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Publication Details

Journal
Biomedicines
Published
2026-04-20
DOI
https://doi.org/10.3390/biomedicines14040936
Primary Topic
Microbial Inactivation Methods
Type
article
Field-Weighted Citation Impact
0.00

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article

Low-Dose Vitamin C-Based Electroporation of Solid Tumors: A New Area in Non-Cytotoxic Electrochemotherapy

Mohammad Abdolahad, Seyed Mojtaba Yazdanparast, Navid Manoochehri
Biomedicines
Microbial Inactivation Methods
article

Low-Dose Vitamin C-Based Electroporation of Solid Tumors: A New Area in Non-Cytotoxic Electrochemotherapy

Mohammad Abdolahad, Seyed Mojtaba Yazdanparast, Navid Manoochehri
article en

Abstract

These findings demonstrate that uniform-field reversible electroporation markedly enhances the intracellular delivery and antitumor activity of low-dose vitamin C, supporting this technology-driven strategy as a promising, low-toxicity alternative to conventional chemotherapeutic agents in electrochemotherapy for solid tumors.

BiomedicinesVol. 14(4)
University of Tehran (IR), Tehran University of Medical Sciences (IR)
Academic Center for Education, Culture and Research
Good health and well-being
Openalex Percentile: Top 18%
Microbial Inactivation Methods
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