<i>In vitro</i> cytocompatibility, antibacterial properties, and hemocompatibility of MAO-Zn/PLA composite films for potential guided bone regeneration treatments
, OCN, ALP, and RUNX2) increased. The hemolysis rate of the composite film was less than 2%. The cell viability in the 1:9 diluted extract was 91.54% and 87.46%, while that in the original extract was only 8.75% and 3.36%, respectively. It is still necessary to further reduce its toxicity by subsequently adjusting its composition and structure. This study provides an experimental basis and theoretical reference for further enhancing the application potential of this kind of composite film in the field of GBR membranes.
Authors
- Shanyun Sun
- Hong Cai (ORCID: https://orcid.org/0000-0003-0932-7774)
- Liu Shijie (ORCID: https://orcid.org/0000-0003-2709-9883)
- Beibei Tang
- Huangqing Zhu
- HaiTao Zhao (ORCID: https://orcid.org/0009-0000-2640-8811)
- Bing Han
- Zhihai Huang
Institutions
- Nanjing Institute of Technology (CN)
- Nanjing Drum Tower Hospital (CN)
- Southeast University (CN)
Publication Details
- Journal
- Biomedical Materials
- Published
- 2026-04-20
- DOI
- https://doi.org/10.1088/1748-605x/ae6214
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China