Structural Features of Highly Bioactive Citrus IntegroPectin Revealed by X‐Ray Diffraction, Fourier Transform Infrared, and Nanoparticle Tracking Analysis
Citrus IntegroPectin denotes a family of flavonoid-pectin bioconjugates with large therapeutic potential sourced via the green extraction CytroCav process consisting of cavitation of industrial citrus processing waste conducted in water only, followed by dialysis and lyophilization or spray-drying. We investigate the structure of lemon, orange, and red (blood) orange IntegroPectin using X-ray diffraction, infrared spectroscopy, and nanoparticle tracking analysis. The analysis unveils several structural nuances unique to this new class of bioconjugates of relevance to forthcoming studies on the use of citrus IntegroPectin for therapy and prevention of numerous diseases.
Authors
- Mario Pagliaro (ORCID: https://orcid.org/0000-0002-5096-329X)
- Rosaria Ciriminna (ORCID: https://orcid.org/0000-0001-6596-1572)
- Caterina Di Sano (ORCID: https://orcid.org/0000-0003-3904-3465)
- Pasquale Picone (ORCID: https://orcid.org/0000-0001-7127-2183)
- Ana R. García (ORCID: https://orcid.org/0000-0001-6289-4554)
- Chiara Valenza (ORCID: https://orcid.org/0000-0003-4544-8960)
- Giuseppe Angellotti (ORCID: https://orcid.org/0000-0001-9226-4748)
- Domenico Nuzzo (ORCID: https://orcid.org/0000-0002-4325-417X)
- Antonella Girgenti
- Francesco Mauriello
- Claudia D’Anna
- Giovanna Li Petri
Institutions
- Institute of Nanostructured Materials (IT)
- Iscte – Instituto Universitário de Lisboa (PT)
- Institute for Biomedical Research and Innovation (IT)
- Istituto di Farmacologia Traslazionale (IT)
- University of Reggio Calabria (IT)
- University of Algarve (PT)
Publication Details
- Journal
- ChemistryOpen
- Published
- 2026-04-20
- DOI
- https://doi.org/10.1002/open.70206
- Primary Topic
- Polysaccharides and Plant Cell Walls
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero dell'Università e della Ricerca