Eliminating Unnecessary Animal Testing

This Perspective reviews the US Food and Drug Administration’s achievements toward eliminating unnecessary animal-based testing and outlines more human-relevant changes for the future.

Authors

Martin A. Makary (ORCID: https://orcid.org/0000-0001-6091-4929)
Tracy Beth Høeg (ORCID: https://orcid.org/0000-0002-2341-6573)
Steven Kozlowski (ORCID: https://orcid.org/0000-0002-7240-3605)
Haleh Saber

Institutions

United States Food and Drug Administration (US)

Publication Details

Journal: JAMA
Published: 2026-04-20
DOI: https://doi.org/10.1001/jama.2026.7074
Primary Topic: Animal testing and alternatives
Type: article
Field-Weighted Citation Impact: 0.00

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article

Eliminating Unnecessary Animal Testing

Martin A. Makary, Tracy Beth Høeg, Steven Kozlowski, Haleh Saber

Apr 20, 2026

JAMA

Animal testing and alternatives

article

Eliminating Unnecessary Animal Testing

Martin A. Makary, Tracy Beth Høeg, Steven Kozlowski, Haleh Saber

April 20, 2026article en

Abstract

This Perspective reviews the US Food and Drug Administration’s achievements toward eliminating unnecessary animal-based testing and outlines more human-relevant changes for the future.

JAMA

United States Food and Drug Administration (US)

Zero hunger

Openalex Percentile: Top 17%

Animal testing and alternatives

DOI Source OpenAlex

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