Interaction of NDRG1 and MRE11 Modulates DNA Replication and Repair
: In summary, our work has uncovered a protein complex between NDRG1 and MRE11 that may play a key role in chemoresistance due to its role in the processing of stalled replication forks.
Authors
- Hanna M. Doh (ORCID: https://orcid.org/0000-0003-0781-611X)
- Philip A. Cole (ORCID: https://orcid.org/0000-0001-6873-7824)
- Taru E. Muranen (ORCID: https://orcid.org/0000-0003-4158-9002)
- Hwan Bae (ORCID: https://orcid.org/0000-0001-5252-252X)
- Zhipeng A. Wang (ORCID: https://orcid.org/0000-0002-5693-7359)
- Nina Kozlova
Institutions
- Brigham and Women's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Dana-Farber Cancer Institute (US)
- Sylvester Comprehensive Cancer Center (US)
Publication Details
- Journal
- Cancers
- Published
- 2026-04-20
- DOI
- https://doi.org/10.3390/cancers18081303
- Primary Topic
- Mechanisms of cancer metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Cancer Society
- Beth Israel Deaconess Medical Center
- National Cancer Institute