Domestic travel as a driver for the dissemination of <i>mcr-1</i> in healthy travelers in China: a prospective, genomic epidemiological and gut microbiome study
. Poultry exposure and gastrointestinal disturbances are key risk factors. Genetic diversity, plasmid transferability, and co-carriage of resistance and virulence determinants highlight the risk of onward spread. Antimicrobial resistance surveillance should extend beyond international travel and incorporate domestic mobility within a "One Health" framework.
Authors
- 敖小军
- Minxuan Su
- C F Chen
- Yushun Chen (ORCID: https://orcid.org/0000-0003-4585-7908)
- Chanjing Zhao
- HoiMan Ng
- Jingwei Shui (ORCID: https://orcid.org/0000-0001-6962-4282)
- Shu’an Wen
- Jiehao Lin
- Jieying Pu (ORCID: https://orcid.org/0000-0002-7473-6972)
- Li Luo (ORCID: https://orcid.org/0000-0002-3883-003X)
- Yueting Jiang
- Meina Wu (ORCID: https://orcid.org/0009-0000-7086-9105)
- Bin Huang
- Zhongde Zhang
- Mingli Hu
- Lingqing Xu (ORCID: https://orcid.org/0009-0004-3068-9344)
- Jianming Zeng
- Hao Wu
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- Kunming Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Kiang Wu Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Antimicrobial Agents and Chemotherapy
- Published
- 2026-04-20
- DOI
- https://doi.org/10.1128/aac.01746-25
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- National Major Science and Technology Projects of China
- Basic and Applied Basic Research Foundation of Guangdong Province