Modulating Cytotoxicity in HeLa Cells <i>via</i> Aromatic Ring Variation in Cu(I) Complexes
chorioallantoic membrane assays demonstrated significant inhibition of neovascularization. Overall, these results establish ligand aromaticity as a key factor governing anticancer activity, providing insight into structure-activity correlations and highlighting the potential of Cu(I) complexes as promising candidates for further anticancer therapeutic development.
Authors
- Shivendra Kumar Pandey (ORCID: https://orcid.org/0000-0002-0996-4573)
- R.J. Butcher
- Vibhav Gautam (ORCID: https://orcid.org/0000-0001-7956-9555)
- Harshita Tiwari (ORCID: https://orcid.org/0009-0006-3665-4649)
- Swati Singh (ORCID: https://orcid.org/0009-0000-2016-7842)
- Riya Kumari
- M.K. Bharty
Institutions
- Howard University (US)
- Czech Academy of Sciences, Institute of Experimental Medicine (CZ)
- Banaras Hindu University (IN)
Publication Details
- Journal
- ACS Applied Bio Materials
- Published
- 2026-04-20
- DOI
- https://doi.org/10.1021/acsabm.6c00151
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Biotechnology, Ministry of Science and Technology, India
- University Grants Commission
- Banaras Hindu University