Non-invasive respiratory support attenuates lung damage in a murine model of bronchopulmonary dysplasia
< 0.0001) in treated mice compared with hyperoxia-exposed controls (60% O₂).These results indicate non-invasive respiratory support not only enhances pulmonary mechanics but also mitigates hyperoxia-induced structural damage, offering insights into its potential application in managing BPD in preterm infants. This study highlights the significance of non-invasive ventilation strategies in reducing the severity of BPD and potentially improving outcomes.
Authors
- Inderpal Randhawa
- Parviz Minoo (ORCID: https://orcid.org/0000-0001-8016-8433)
- Nathan L. Marsteller (ORCID: https://orcid.org/0000-0001-6243-4312)
- Beiyun Zhou (ORCID: https://orcid.org/0000-0002-9084-5933)
- Changgong Li (ORCID: https://orcid.org/0000-0002-8534-8190)
- Anh Duong
- Jitendra K. Tripathi
Institutions
- University of Southern California (US)
- Hastings Center (US)
- LAC+USC Medical Center (US)
- Memorial Health System (US)
- Memorial Health System (US)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2026-04-20
- DOI
- https://doi.org/10.3389/fped.2026.1755113
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Southern California