Charcot Neuro-Osteoarthropathy: A new Risk Class is Needed?

prevalence was higher in HR patients, revascularization rates among those with PAD were higher in the CNO cohort, likely reflecting differences in referral thresholds and care pathways rather than PAD prevalence alone. In Year 2, intensified surveillance in CNO patients was associated with a marked reduction in re-ulceration (18.5% vs 70.4%); trends towards fewer amputations and revascularizations were observed.ConclusionChronic CNO appears to represent a distinct high-risk recurrence phenotype not fully reflected by current IWGDF risk stratification. While limited by sample size and single-centre design, these findings support further evaluation of CNO-specific surveillance strategies and consideration of CNO as a separate risk stratum within the IWGDF framework.

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Publication Details

Journal
The International Journal of Lower Extremity Wounds
Published
2026-04-20
DOI
https://doi.org/10.1177/15347346261440782
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Charcot Neuro-Osteoarthropathy: A new Risk Class is Needed?

S. Viti, Roberto Anichini, On behalf of the diabetic podopathy team of Area Pistoiese, Marco Perini et al.
The International Journal of Lower Extremity Wounds
Diabetic Foot Ulcer Assessment and Management
article

Charcot Neuro-Osteoarthropathy: A new Risk Class is Needed?

S. Viti, Roberto Anichini, On behalf of the diabetic podopathy team of Area Pistoiese, Marco Perini, Andrea Mancini
article en

Abstract

prevalence was higher in HR patients, revascularization rates among those with PAD were higher in the CNO cohort, likely reflecting differences in referral thresholds and care pathways rather than PAD prevalence alone. In Year 2, intensified surveillance in CNO patients was associated with a marked reduction in re-ulceration (18.5% vs 70.4%); trends towards fewer amputations and revascularizations were observed.ConclusionChronic CNO appears to represent a distinct high-risk recurrence phenotype not fully reflected by current IWGDF risk stratification. While limited by sample size and single-centre design, these findings support further evaluation of CNO-specific surveillance strategies and consideration of CNO as a separate risk stratum within the IWGDF framework.

The International Journal of Lower Extremity Wounds
Azienda Usl Toscana Centro (IT)
Openalex Percentile: Top 11%
Diabetic Foot Ulcer Assessment and Management
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