Evaluating Clinically Meaningful Improvement in Addiction and Mental Health Symptoms in Inpatient Programming

OBJECTIVE: The current project examined the effectiveness of an inpatient treatment center by evaluating clinically significant improvements across measures of functional impairment, addiction-related symptoms, traumatic stress, and psychological distress. METHODS: = 537) comprised individuals who completed either a 7-week or 9-week inpatient program for addiction and mental health. RESULTS: Over 75% of participants met the cutoff for clinical improvement based on established reliable change indices on measures of overall functioning and depression. Over 80% met the clinical improvement cutoff for measures of posttraumatic stress and substance dependence. About 61% had clinical improvement on measures of anxiety. Significant reductions in symptoms of anxiety, depression, traumatic stress, substance dependence, and functional impairment were observed from admission to discharge. Change scores on the four outcome measures were significantly related to the decreased likelihood of being classified as "reliably better" compared to "no change" in overall functioning post-treatment completion. Change scores on all variables, except anxiety symptoms, demonstrated no significant relationship with the likelihood of being classified as "reliably worse" in overall functioning post-treatment completion compared to "no change." CONCLUSION: Findings support the positive impact of inpatient treatments that adopt integrated care approaches for both individuals with SUD and co-occurring psychological conditions.

Authors

Institutions

Publication Details

Journal
Substance Use & Misuse
Published
2026-04-20
DOI
https://doi.org/10.1080/10826084.2026.2648153
Primary Topic
Substance Abuse Treatment and Outcomes
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Evaluating Clinically Meaningful Improvement in Addiction and Mental Health Symptoms in Inpatient Programming

Samantha R. Pejic, Lindsey A. Snaychuk, Tisha J. Ornstein, Christina A. Basedow et al.
Substance Use & Misuse
Substance Abuse Treatment and Outcomes
article

Evaluating Clinically Meaningful Improvement in Addiction and Mental Health Symptoms in Inpatient Programming

Samantha R. Pejic, Lindsey A. Snaychuk, Tisha J. Ornstein, Christina A. Basedow, Maya Thulin, Sarah Swan
article en

Abstract

OBJECTIVE: The current project examined the effectiveness of an inpatient treatment center by evaluating clinically significant improvements across measures of functional impairment, addiction-related symptoms, traumatic stress, and psychological distress. METHODS: = 537) comprised individuals who completed either a 7-week or 9-week inpatient program for addiction and mental health. RESULTS: Over 75% of participants met the cutoff for clinical improvement based on established reliable change indices on measures of overall functioning and depression. Over 80% met the clinical improvement cutoff for measures of posttraumatic stress and substance dependence. About 61% had clinical improvement on measures of anxiety. Significant reductions in symptoms of anxiety, depression, traumatic stress, substance dependence, and functional impairment were observed from admission to discharge. Change scores on the four outcome measures were significantly related to the decreased likelihood of being classified as "reliably better" compared to "no change" in overall functioning post-treatment completion. Change scores on all variables, except anxiety symptoms, demonstrated no significant relationship with the likelihood of being classified as "reliably worse" in overall functioning post-treatment completion compared to "no change." CONCLUSION: Findings support the positive impact of inpatient treatments that adopt integrated care approaches for both individuals with SUD and co-occurring psychological conditions.

Substance Use & Misuse
All Nations Hope Network (CA), Toronto Metropolitan University (CA)
Mitacs
Good health and well-being
Openalex Percentile: Top 10%
Substance Abuse Treatment and Outcomes
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.