Predicting long-term clinical mortality of elderly patients with vertebral compression fractures

< 0.001). Calibration curves and decision curve analysis further validated the model's clinical utility. The XGB model's interpretability was enhanced using SHAP values, providing insights into the influence of individual features on mortality risk. In conclusion, we developed a novel risk-stratification model for predicting mortality for VCFs. Our model can also aid in stratifying patients, with high discriminative ability. The use of an explainable machine learning model can aid physicians in making individualized treatment decision in VCFs patients.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-04-21
DOI
https://doi.org/10.3389/fmed.2026.1708134
Primary Topic
Spinal Fractures and Fixation Techniques
Type
article
Field-Weighted Citation Impact
0.00
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article

Predicting long-term clinical mortality of elderly patients with vertebral compression fractures

Shuofan Wang, Kaiwen Peng, Kaili Peng, Zhichao Gao
Frontiers in Medicine
Spinal Fractures and Fixation Techniques
article

Predicting long-term clinical mortality of elderly patients with vertebral compression fractures

Shuofan Wang, Kaiwen Peng, Kaili Peng, Zhichao Gao
article en

Abstract

< 0.001). Calibration curves and decision curve analysis further validated the model's clinical utility. The XGB model's interpretability was enhanced using SHAP values, providing insights into the influence of individual features on mortality risk. In conclusion, we developed a novel risk-stratification model for predicting mortality for VCFs. Our model can also aid in stratifying patients, with high discriminative ability. The use of an explainable machine learning model can aid physicians in making individualized treatment decision in VCFs patients.

Frontiers in MedicineVol. 13
Air Liquide (United Kingdom) (GB), Linzi District People's Hospital (CN)
Reduced inequalities
Openalex Percentile: Top 23%
Spinal Fractures and Fixation Techniques
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