Off‑the‑shelf and on‑target: how iPSC‑derived CAR‑T cells could democratize autoimmune cell therapy

“The future of autoimmunity is being reprogrammed in real time, and iPSC CAR‑T cells are helping to write the code.”Abi Pinchbeck, Commissioning Editor, Cell & Gene Therapy Insights, speaks with John (Bobby) Goulding, Director, Corporate Strategy, Fate Therapeutics, who takes an in‑depth look at induced pluripotent stem cell (iPSC)-derived allogeneic CAR‑T cells and their potential clinical application in autoimmune disease, including safety‑by‑design considerations, clinical trial considerations, manufacturing scalability, and democratizing outpatient access.

Authors

Publication Details

Journal
Cell and Gene Therapy Insights
Published
2026-04-14
DOI
https://doi.org/10.18609/cgti.2026.033
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Off‑the‑shelf and on‑target: how iPSC‑derived CAR‑T cells could democratize autoimmune cell therapy

John Goulding
Cell and Gene Therapy Insights
CAR-T cell therapy research
article

Off‑the‑shelf and on‑target: how iPSC‑derived CAR‑T cells could democratize autoimmune cell therapy

John Goulding
article en

Abstract

“The future of autoimmunity is being reprogrammed in real time, and iPSC CAR‑T cells are helping to write the code.”Abi Pinchbeck, Commissioning Editor, Cell & Gene Therapy Insights, speaks with John (Bobby) Goulding, Director, Corporate Strategy, Fate Therapeutics, who takes an in‑depth look at induced pluripotent stem cell (iPSC)-derived allogeneic CAR‑T cells and their potential clinical application in autoimmune disease, including safety‑by‑design considerations, clinical trial considerations, manufacturing scalability, and democratizing outpatient access.

Cell and Gene Therapy InsightsVol. 12(3)
Openalex Percentile: Top 7%
CAR-T cell therapy research
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