Herbal Alchemy: The Convergence of Plant-Derived Extracts andNanotechnology in the Synthesis of Silver Nanoparticles and TherapeuticsApplications

Sustainable and effective medicinal treatments have entered a new age with the advent of Nanotechnology (NT) and green chemistry. By harnessing the bioactive characteristics of phytochemicals obtained from plants, plant-based production of silver nanoparticles (AgNPs) provides a safer, more economical, and less harmful alternative to traditional physical and chemical procedures. This review summarizes the main processes, phytochemical interactions, and morphological aspects that are prerequisites for the generation of plants-mediated AgNPs, which could reveal their revolutionary potential. Their unique physicochemical characteristics and biocompatibility prove the superlative antibacterial, anti-inflammatory, antiviral, antifungal, and anticancer activities of such AgNPs. In the spirit of green chemistry, these nanoparticles minimise the impact on environmental terms, thus showing a better therapeutic effectiveness. Among other examples of their versatility in modern medicine, their newly developed applications are in diagnostic imaging, targeted medication, and wound healing. This is a review of the fundamental processes, phytochemical interactions, and morphological aspects that are prerequisites for the generation of plant-mediated AgNPs, which could reveal their revolutionary potential. Their unique physicochemical characteristics and biocompatibility demonstrate the superlative antibacterial, anti-inflammatory, antiviral, antifungal, and anticancer activities of these AgNPs. In the spirit of green chemistry, these nanoparticles minimise environmental impact, thereby demonstrating better therapeutic effectiveness. Among other examples of their versatility in modern medicine, their newly developed applications include diagnostic imaging, targeted medication, and wound healing. Modern advances in synthesis methods, characterisation tools, and therapeutic uses are discussed in this article, with a focus on how plant diversity might be used to customize the activity of NPs. The article highlights how plant diversity can be used to customise nanoparticle functionality and discusses the opportunities and challenges of translating herbal AgNPs into clinical personalised medicine. The use of plant-based AgNPs signifies a significant change in thinking about sustainable nanomedicine, as they combine the best of both traditional herbal medicines and modern NT.

Authors

Institutions

Publication Details

Journal
Drug Delivery Letters
Published
2026-04-14
DOI
https://doi.org/10.2174/0122103031425154260324060148
Primary Topic
Nanoparticles: synthesis and applications
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Herbal Alchemy: The Convergence of Plant-Derived Extracts andNanotechnology in the Synthesis of Silver Nanoparticles and TherapeuticsApplications

H. S. Sagar, G. B. Kiran Kumar, B.K. Madhu, Naik Prasiddhi et al.
Drug Delivery Letters
Nanoparticles: synthesis and applications
article

Herbal Alchemy: The Convergence of Plant-Derived Extracts andNanotechnology in the Synthesis of Silver Nanoparticles and TherapeuticsApplications

H. S. Sagar, G. B. Kiran Kumar, B.K. Madhu, Naik Prasiddhi, Prakash Goudanavar, H. N. Rohan, B. Prakash kumar
article en

Abstract

Sustainable and effective medicinal treatments have entered a new age with the advent of Nanotechnology (NT) and green chemistry. By harnessing the bioactive characteristics of phytochemicals obtained from plants, plant-based production of silver nanoparticles (AgNPs) provides a safer, more economical, and less harmful alternative to traditional physical and chemical procedures. This review summarizes the main processes, phytochemical interactions, and morphological aspects that are prerequisites for the generation of plants-mediated AgNPs, which could reveal their revolutionary potential. Their unique physicochemical characteristics and biocompatibility prove the superlative antibacterial, anti-inflammatory, antiviral, antifungal, and anticancer activities of such AgNPs. In the spirit of green chemistry, these nanoparticles minimise the impact on environmental terms, thus showing a better therapeutic effectiveness. Among other examples of their versatility in modern medicine, their newly developed applications are in diagnostic imaging, targeted medication, and wound healing. This is a review of the fundamental processes, phytochemical interactions, and morphological aspects that are prerequisites for the generation of plant-mediated AgNPs, which could reveal their revolutionary potential. Their unique physicochemical characteristics and biocompatibility demonstrate the superlative antibacterial, anti-inflammatory, antiviral, antifungal, and anticancer activities of these AgNPs. In the spirit of green chemistry, these nanoparticles minimise environmental impact, thereby demonstrating better therapeutic effectiveness. Among other examples of their versatility in modern medicine, their newly developed applications include diagnostic imaging, targeted medication, and wound healing. Modern advances in synthesis methods, characterisation tools, and therapeutic uses are discussed in this article, with a focus on how plant diversity might be used to customize the activity of NPs. The article highlights how plant diversity can be used to customise nanoparticle functionality and discusses the opportunities and challenges of translating herbal AgNPs into clinical personalised medicine. The use of plant-based AgNPs signifies a significant change in thinking about sustainable nanomedicine, as they combine the best of both traditional herbal medicines and modern NT.

Drug Delivery LettersVol. 16
Rajiv Gandhi University of Health Sciences (IN)
Responsible consumption and production
Openalex Percentile: Top 11%
Nanoparticles: synthesis and applications
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.