Investigation of correlates of protection against gonococcal infection by comparative immunoprofiling of responses in experimental and clinical studies
Meningococcal OMV vaccination confers cross-protection against gonococcal infection, and induces systemic and mucosal IgG signatures, with responses in mice reflecting those in human vaccinees. Protection in mice was associated with early PMN influx in the genital tract following infection.
Authors
- Ann E. Jerse (ORCID: https://orcid.org/0000-0002-5118-3172)
- Rebekah A. Jones (ORCID: https://orcid.org/0000-0002-4038-1798)
- Samantha A McKeand (ORCID: https://orcid.org/0000-0001-5579-7422)
- Angela Thistlethwaite
- ZhenYi Gu
- Jeremy P. Derrick (ORCID: https://orcid.org/0000-0002-4350-5354)
- Anthony Soc
- Christoph Tang
- Eduard J. Sanders
- Eunice Nduati
- Fidel; id_orcid 0000-0001-8215-0843 Ramirez Bencomo
Institutions
- Genomics (United Kingdom) (GB)
Publication Details
- Journal
- Research Explorer (The University of Manchester)
- Published
- 2026-04-10
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00