Edge-First Genomics: Why the Lab of the Future Processes Data Locally

Position paper arguing that genomic data processing must shift from cloud-centralized to edge-first architectures. Examines data sovereignty implications of cross-border genomic transfers under GDPR and the CLOUD Act. Proposes local-first processing pipelines where raw sequencing data never leaves the facility, with only differential privacy-protected aggregates shared for federated research.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-04-21
DOI
https://doi.org/10.5281/zenodo.19643349
Primary Topic
Evolutionary Algorithms and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Edge-First Genomics: Why the Lab of the Future Processes Data Locally

Zenodo (CERN European Organization for Nuclear Research)
Evolutionary Algorithms and Applications
article

Edge-First Genomics: Why the Lab of the Future Processes Data Locally

article en

Abstract

Position paper arguing that genomic data processing must shift from cloud-centralized to edge-first architectures. Examines data sovereignty implications of cross-border genomic transfers under GDPR and the CLOUD Act. Proposes local-first processing pipelines where raw sequencing data never leaves the facility, with only differential privacy-protected aggregates shared for federated research.

Zenodo (CERN European Organization for Nuclear Research)
Association of British Orchestras (GB)
Openalex Percentile: Top 12%
Evolutionary Algorithms and Applications
DOIOpen Access PDFOpenAlex
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Edge-First Genomics: Why the Lab of the Future Processes Data Locally · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS