An Uncommon Presentation of a Solid Pseudopapillary Neoplasm in a Male Patient: Diagnostic Challenges and Multidisciplinary Management of a Pancreatic Tail Mass
Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor that typically affects young women and has a low malignant potential. We report the case of a 37-year-old man who was being investigated for secondary hypertension when imaging revealed a pancreatic tail mass. Radiological findings suggested a differential diagnosis including SPN, cystic adenocarcinoma, or a mesenchymal tumor. Further evaluation with MRI, PET, and histopathology confirmed the diagnosis of SPN. The patient underwent successful robotic distal pancreatectomy with splenectomy and was found to have an R0 resection with no nodal involvement. This case highlights the importance of a multidisciplinary approach and maintaining a broad differential diagnosis, even in atypical patient populations.
Authors
- Mohamed Lameir Mukhtar Hussein
- Rana Shalaby (ORCID: https://orcid.org/0009-0007-1564-2849)
- Sarah Sayed
- Khadija Jaffar KI Radwani
Publication Details
- Journal
- Cureus
- Published
- 2026-04-17
- DOI
- https://doi.org/10.7759/cureus.107270
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00