Study of the possibility of isolating atazanavir from biological fluids for the purpose of chemical-toxicological analysis

The article presents the results of developing optimal conditions for extracting atazanavir using liquid-liquid extraction from physiological fluids (urine, saliva, and blood plasma), as well as identifying and quantifying this substance in extracts using thin-layer chromatography, UV spectrophotometry, and high-performance liquid chromatography.

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Publication Details

Journal
Forensic Medical Expertise
Published
2026-04-17
DOI
https://doi.org/10.17116/sudmed20266902132
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Study of the possibility of isolating atazanavir from biological fluids for the purpose of chemical-toxicological analysis

N. V. СHMЕLЕVSKАYА, E.A. Illarionova, V.A. Zherbakova
Forensic Medical Expertise
HIV/AIDS drug development and treatment
article

Study of the possibility of isolating atazanavir from biological fluids for the purpose of chemical-toxicological analysis

N. V. СHMЕLЕVSKАYА, E.A. Illarionova, V.A. Zherbakova
article en

Abstract

The article presents the results of developing optimal conditions for extracting atazanavir using liquid-liquid extraction from physiological fluids (urine, saliva, and blood plasma), as well as identifying and quantifying this substance in extracts using thin-layer chromatography, UV spectrophotometry, and high-performance liquid chromatography.

Forensic Medical ExpertiseVol. 69(2)
Irkutsk Regional Clinical Hospital (RU), Irkutsk State Medical University (RU)
Openalex Percentile: Top 8%
HIV/AIDS drug development and treatment
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