Short-term predictors of morbidity and mortality after surgery for transposition of the great arteries

BACKGROUND: Dextro-transposition of the great arteries is one of the most common cyanotic congenital heart diseases in newborns. Today's first-choice surgery is the arterial switch. This study aims to analyze predictors (<30 postoperative days) of short-term morbidity and mortality after arterial switch at HUDERF and to compare them between simple (without VSD) and complex transpositions (with VSD with/without left/right ventricular outflow tract obstruction or aortic arch anomalies) and between premature and full-term newborns. METHODS: A retrospective single-center cohort study was conducted, reviewing the records of patients with transposition of the great arteries operated at HUDERF between 1997-2023. Patients were divided into simple and complex transpositions, and premature and full-term newborns. RESULTS: = 0.048). CONCLUSIONS: Early morbidity, early mortality and reoperation rates were higher in complex transpositions, particularly among premature newborns. Heart failure and pulmonary stenosis were the most common early complications. Heart failure was the main factor associated with early mortality. Pulmonary stenosis was one of the most frequent causes of reoperations.

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Publication Details

Journal
Acta chirurgica Belgica
Published
2026-04-17
DOI
https://doi.org/10.1080/00015458.2026.2659698
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

Short-term predictors of morbidity and mortality after surgery for transposition of the great arteries

Pierre Wauthy, Cynthia Chan
Acta chirurgica Belgica
Congenital Heart Disease Studies
article

Short-term predictors of morbidity and mortality after surgery for transposition of the great arteries

Pierre Wauthy, Cynthia Chan
article en

Abstract

BACKGROUND: Dextro-transposition of the great arteries is one of the most common cyanotic congenital heart diseases in newborns. Today's first-choice surgery is the arterial switch. This study aims to analyze predictors (<30 postoperative days) of short-term morbidity and mortality after arterial switch at HUDERF and to compare them between simple (without VSD) and complex transpositions (with VSD with/without left/right ventricular outflow tract obstruction or aortic arch anomalies) and between premature and full-term newborns. METHODS: A retrospective single-center cohort study was conducted, reviewing the records of patients with transposition of the great arteries operated at HUDERF between 1997-2023. Patients were divided into simple and complex transpositions, and premature and full-term newborns. RESULTS: = 0.048). CONCLUSIONS: Early morbidity, early mortality and reoperation rates were higher in complex transpositions, particularly among premature newborns. Heart failure and pulmonary stenosis were the most common early complications. Heart failure was the main factor associated with early mortality. Pulmonary stenosis was one of the most frequent causes of reoperations.

Acta chirurgica Belgica
Université Libre de Bruxelles (BE)
Good health and well-being
Openalex Percentile: Top 12%
Congenital Heart Disease Studies
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