Discovery and Development of First-in-Class Cereblon-Recruiting RIPK1 Degraders

as a chemical probe for studying RIPK1 biology and a promising candidate for cancer treatment.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-04-14
DOI
https://doi.org/10.64898/2026.04.10.717852
Primary Topic
Protein Degradation and Inhibitors
Type
article
Field-Weighted Citation Impact
0.00
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article

Discovery and Development of First-in-Class Cereblon-Recruiting RIPK1 Degraders

Dong Lu, Jingjing Chen, Feng Li, Min Zhang et al.
bioRxiv (Cold Spring Harbor Laboratory)
Protein Degradation and Inhibitors
article

Discovery and Development of First-in-Class Cereblon-Recruiting RIPK1 Degraders

Dong Lu, Jingjing Chen, Feng Li, Min Zhang, Ran Cheng, Xiaoli Qi, Bin Yang, Hanfeng Lin, Xin Yu
article en

Abstract

as a chemical probe for studying RIPK1 biology and a promising candidate for cancer treatment.

bioRxiv (Cold Spring Harbor Laboratory)
Baylor College of Medicine (US)
Openalex Percentile: Top 23%
Protein Degradation and Inhibitors
DOIOpen Access PDFOpenAlex
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Discovery and Development of First-in-Class Cereblon-Recruiting RIPK1 Degraders — Dong Lu, Jingjing Chen, et al. · bioRxiv (Cold Spring Harbor Laboratory) (2026) | TGRS Research Map | TGRS