Integrative Bulk and Single-Nucleus Analyses Nominate COL5A2 as a CAF/ECM-Associated Marker Associated with PDAC Progression
: COL5A2 is a reproducible stromal/ECM-associated candidate biomarker linked to PDAC progression, with predominant expression in fibroblast/CAF compartments.
Authors
- Ju‐Fang Liu (ORCID: https://orcid.org/0000-0002-0887-6096)
- Tsung-Ming Chang
- Kuan-Ting Lu
- Chi-Jen Chang
Institutions
- Fu Jen Catholic University (TW)
- China Medical University (TW)
- China Medical University Hospital (TW)
- Memorial Hospital (US)
- Taipei Medical University (TW)
Publication Details
- Journal
- Diagnostics
- Published
- 2026-04-17
- DOI
- https://doi.org/10.3390/diagnostics16081205
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shin Kong Wu Ho-Su Memorial Hospital
- Ministry of Science and Technology, Taiwan