Pyridine- and quinoline-based piperazine nitriles: Potent and selective 5-HT3 receptor agonists and efficacious desensitizers
R-selectivity and the potent and efficacious receptor desensitization induced by 6a make it a potentially interesting pharmacological tool for studies of these receptors.
Authors
- Anders A. Jensen (ORCID: https://orcid.org/0000-0002-7927-5052)
Institutions
- University of Copenhagen (DK)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2026-04-17
- DOI
- https://doi.org/10.1016/j.biopha.2026.119351
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Københavns Universitet
- Lundbeckfonden