Establishment of a multi-targeted magnetic combined enrichment system for circulating tumor cells in gastric cancer and analysis of their genomic profiles

This study successfully established a multi-target combined CTCs multi-targeted magnetic combined sorting system for GC. CTCs detection based on this system can be used for the auxiliary diagnosis of GC patients. Furthermore, compared to GC tissue and ctDNA samples, CTCs detection enables more comprehensive genomic profiling analysis and serves as an important supplement to GC genomic analysis.

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Publication Details

Journal
Journal of Biomaterials Applications
Published
2026-04-17
DOI
https://doi.org/10.1177/08853282261443671
Primary Topic
Cancer Cells and Metastasis
Type
article
Field-Weighted Citation Impact
0.00
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article

Establishment of a multi-targeted magnetic combined enrichment system for circulating tumor cells in gastric cancer and analysis of their genomic profiles

Yuelu Ruan, J H Xu, Lei Zhu
Journal of Biomaterials Applications
Cancer Cells and Metastasis
article

Establishment of a multi-targeted magnetic combined enrichment system for circulating tumor cells in gastric cancer and analysis of their genomic profiles

Yuelu Ruan, J H Xu, Lei Zhu
article en

Abstract

This study successfully established a multi-target combined CTCs multi-targeted magnetic combined sorting system for GC. CTCs detection based on this system can be used for the auxiliary diagnosis of GC patients. Furthermore, compared to GC tissue and ctDNA samples, CTCs detection enables more comprehensive genomic profiling analysis and serves as an important supplement to GC genomic analysis.

Journal of Biomaterials Applications
Wuhan Third Hospital (CN), Wuhan University of Science and Technology (CN)
Openalex Percentile: Top 13%
Cancer Cells and Metastasis
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