Research on segmentation method of elderly cardiovascular disease feature images based on artificial intelligence multi-scale feature fusion

Accurate segmentation of medical images is crucial for diagnosing and treating cardiovascular diseases in the elderly. However, these images often suffer from blurred boundaries and low contrast due to complex lesions such as calcification and plaque, challenging existing methods to simultaneously capture global context and preserve local details. To address this, we propose CTM-Net, a collaborative framework integrating convolutional neural networks (CNNs), transformers, and multilayer perceptrons (MLPs). The CNN encoder extracts hierarchical local features, a Transformer module at the bottleneck captures long-range dependencies, and a lightweight MLP-based decoder with a novel Spatial-Channel MLP (SC-MLP) block performs efficient upsampling and pixel-level classification. Multi-scale feature fusion is achieved via skip connections. Experiments on three public cardiovascular datasets (ASOCA, Cardiac-MRI, Sunnybrook) demonstrate that our method significantly outperforms mainstream models like U-Net, TransUNet, and nnUNet in key metrics (e.g., 82.1% Dice on ASOCA vs. 81.5% for nnUNet, p < 0.05), while maintaining superior computational efficiency. Systematic ablation studies validate the synergistic design. This framework offers a promising pathway for complex cardiovascular image segmentation.

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Publication Details

Journal
Scientific Reports
Published
2026-04-17
DOI
https://doi.org/10.1038/s41598-026-49091-0
Primary Topic
Advanced Neural Network Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Research on segmentation method of elderly cardiovascular disease feature images based on artificial intelligence multi-scale feature fusion

Li Wei, Ma Fangfang, Peng Longhua, Bian Chen et al.
Scientific Reports
Advanced Neural Network Applications
article

Research on segmentation method of elderly cardiovascular disease feature images based on artificial intelligence multi-scale feature fusion

Li Wei, Ma Fangfang, Peng Longhua, Bian Chen, Zhao Cheng, Cheng Cheng
article en

Abstract

Accurate segmentation of medical images is crucial for diagnosing and treating cardiovascular diseases in the elderly. However, these images often suffer from blurred boundaries and low contrast due to complex lesions such as calcification and plaque, challenging existing methods to simultaneously capture global context and preserve local details. To address this, we propose CTM-Net, a collaborative framework integrating convolutional neural networks (CNNs), transformers, and multilayer perceptrons (MLPs). The CNN encoder extracts hierarchical local features, a Transformer module at the bottleneck captures long-range dependencies, and a lightweight MLP-based decoder with a novel Spatial-Channel MLP (SC-MLP) block performs efficient upsampling and pixel-level classification. Multi-scale feature fusion is achieved via skip connections. Experiments on three public cardiovascular datasets (ASOCA, Cardiac-MRI, Sunnybrook) demonstrate that our method significantly outperforms mainstream models like U-Net, TransUNet, and nnUNet in key metrics (e.g., 82.1% Dice on ASOCA vs. 81.5% for nnUNet, p < 0.05), while maintaining superior computational efficiency. Systematic ablation studies validate the synergistic design. This framework offers a promising pathway for complex cardiovascular image segmentation.

Scientific Reports
Xuzhou Medical College (CN), Xuzhou No.1 People's Hospital (CN)
Openalex Percentile: Top 5%
Advanced Neural Network Applications
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