The Role of the Gut Microbiota and Uraemic Toxins in Vaccine Responsiveness Among People Receiving Maintenance Haemodialysis
: Differences in gut microbial composition were observed between vaccine responder groups, while uraemic toxin concentrations were not associated with vaccine responsiveness. These findings suggest gut microbiota composition may contribute to vaccine hypo-responsiveness in individuals receiving dialysis and warrant further investigation in larger mechanistic studies.
Authors
- Griffith B. Perkins (ORCID: https://orcid.org/0000-0001-8559-5872)
- Bree Shi (ORCID: https://orcid.org/0000-0003-2745-7011)
- Steven J. Chadban (ORCID: https://orcid.org/0000-0002-0527-898X)
- Erin Vaughan (ORCID: https://orcid.org/0009-0008-4071-7475)
- Alexander Gilbert
- Huiling Wu
Institutions
- The University of Sydney (AU)
- Royal Adelaide Hospital (AU)
- Royal Prince Alfred Hospital (AU)
- The University of Adelaide (AU)
Publication Details
- Journal
- Vaccines
- Published
- 2026-04-17
- DOI
- https://doi.org/10.3390/vaccines14040358
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00