Microneedle assisted drug delivery of liposome loaded with selegiline hydrochloride for effective management of Parkinson’s disease intervention

antiparkinson disease study. Biochemical tests supported these findings by showing increased antioxidant enzyme activity, reduced lipid peroxidation, and a noticeable rise in dopamine levels in brain tissue. A histopathological study showed improved neuronal regeneration for the SH-LP3-MNP formulation. Through these findings, it was reported that the SH-LP3-MNP formulation is a promising approach for delivering liposomes loaded with selegiline through the skin for the treatment of Parkinson's disease symptoms.

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Publication Details

Journal
Journal of Liposome Research
Published
2026-04-17
DOI
https://doi.org/10.1080/08982104.2026.2657323
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00
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article

Microneedle assisted drug delivery of liposome loaded with selegiline hydrochloride for effective management of Parkinson’s disease intervention

Jobin Jose, Kartik Bhairu Khot, Shridhar Deshpande N, Naseer Maliyakkal et al.
Journal of Liposome Research
Advancements in Transdermal Drug Delivery
article

Microneedle assisted drug delivery of liposome loaded with selegiline hydrochloride for effective management of Parkinson’s disease intervention

Jobin Jose, Kartik Bhairu Khot, Shridhar Deshpande N, Naseer Maliyakkal, Ketura Kambampaty, Akshay Bandiwadekar, Gopika Gopan
article en

Abstract

antiparkinson disease study. Biochemical tests supported these findings by showing increased antioxidant enzyme activity, reduced lipid peroxidation, and a noticeable rise in dopamine levels in brain tissue. A histopathological study showed improved neuronal regeneration for the SH-LP3-MNP formulation. Through these findings, it was reported that the SH-LP3-MNP formulation is a promising approach for delivering liposomes loaded with selegiline through the skin for the treatment of Parkinson's disease symptoms.

Journal of Liposome Research
Nitte University (IN), University of Pharmacy Mandalay (MM), King Khalid University (SA)
Good health and well-being
Openalex Percentile: Top 14%
Advancements in Transdermal Drug Delivery
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