Microneedle assisted drug delivery of liposome loaded with selegiline hydrochloride for effective management of Parkinson’s disease intervention
antiparkinson disease study. Biochemical tests supported these findings by showing increased antioxidant enzyme activity, reduced lipid peroxidation, and a noticeable rise in dopamine levels in brain tissue. A histopathological study showed improved neuronal regeneration for the SH-LP3-MNP formulation. Through these findings, it was reported that the SH-LP3-MNP formulation is a promising approach for delivering liposomes loaded with selegiline through the skin for the treatment of Parkinson's disease symptoms.
Authors
- Jobin Jose (ORCID: https://orcid.org/0000-0002-2815-5384)
- Kartik Bhairu Khot
- Shridhar Deshpande N
- Naseer Maliyakkal (ORCID: https://orcid.org/0000-0001-6682-3876)
- Ketura Kambampaty
- Akshay Bandiwadekar
- Gopika Gopan
Institutions
- Nitte University (IN)
- University of Pharmacy Mandalay (MM)
- King Khalid University (SA)
Publication Details
- Journal
- Journal of Liposome Research
- Published
- 2026-04-17
- DOI
- https://doi.org/10.1080/08982104.2026.2657323
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00