The Efficacy of Dexmedetomidine Versus Ketamine for Sedation in Pediatric Dental Procedures: A Systematic Review and Meta-Analysis

Based on limited and clinically heterogeneous evidence, both dexmedetomidine and ketamine appear to be viable options for sedation in pediatric dental settings, though no firm superiority conclusion can be drawn. Further randomized controlled trials with larger sample sizes and standardized sedation protocols are recommended to strengthen these findings and inform practice guidelines.

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Publication Details

Journal
Children
Published
2026-04-17
DOI
https://doi.org/10.3390/children13040558
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
0.00
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article

The Efficacy of Dexmedetomidine Versus Ketamine for Sedation in Pediatric Dental Procedures: A Systematic Review and Meta-Analysis

Shahad N. Abudawood, Narmin Helal, Heba Jafar Sabbagh, AbdulRahman Alasmri et al.
Children
Anesthesia and Sedative Agents
article

The Efficacy of Dexmedetomidine Versus Ketamine for Sedation in Pediatric Dental Procedures: A Systematic Review and Meta-Analysis

Shahad N. Abudawood, Narmin Helal, Heba Jafar Sabbagh, AbdulRahman Alasmri, Ali Alhijab
article en

Abstract

Based on limited and clinically heterogeneous evidence, both dexmedetomidine and ketamine appear to be viable options for sedation in pediatric dental settings, though no firm superiority conclusion can be drawn. Further randomized controlled trials with larger sample sizes and standardized sedation protocols are recommended to strengthen these findings and inform practice guidelines.

ChildrenVol. 13(4)
King Abdulaziz University (SA)
Partnerships for the goals
Openalex Percentile: Top 20%
Anesthesia and Sedative Agents
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