Impact of relaxation training and sedative medication use on respiratory recovery in hospitalized patients with respiratory diseases: a retrospective observational study

Background: Psychological distress and sedative medication exposure are common among hospitalized patients with respiratory diseases and may influence clinical recovery. However, evidence regarding the combined impact of relaxation training and medication use on respiratory outcomes remains limited. This study aimed to examine the association between relaxation training, sedative or psychotropic medication use, and respiratory recovery in patients hospitalized with respiratory diseases. Methods: ≥ 60 mmHg on room air when an arterial blood gas test was available within 24 h before discharge). Variables associated with recovery were identified using univariate and multivariable logistic regression analyses. Model discrimination, calibration, and clinical utility were assessed by the concordance index (C-index), Hosmer-Lemeshow test, calibration plot, and decision curve analysis. Results: = 0.582). Decision curve analysis indicated a higher net clinical benefit of the model across relevant probability thresholds. Conclusion: In this retrospective cohort of hospitalized patients with respiratory diseases, engagement in relaxation training was independently associated with improved respiratory recovery, whereas early sedative medication exposure predicted poorer outcomes. Psychological and physiological parameters jointly influenced recovery probability. These findings underscore the importance of integrating psychological relaxation interventions and cautious sedative management in the clinical care of respiratory patients.