Two-year clinical outcomes of standalone gonioscopy-assisted transluminal trabeculotomy in normal-tension glaucoma

Purpose: To evaluate the 2-year efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) for normal-tension glaucoma (NTG). Methods: tests or Wilcoxon signed-rank tests were used as appropriate; a one-eye-per-patient sensitivity analysis was performed. Results: = 9) was consistent. No hypotony, IOP spikes, or serious complications occurred. Events were mild and self-limited (mainly hyphema and aqueous flare). No SLT, needling, or additional glaucoma surgery was required. Conclusion: GATT significantly reduced IOP and medication burden in NTG with a safety profile through 24 months. Larger prospective studies are warranted.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-04-17
DOI
https://doi.org/10.3389/fmed.2026.1828249
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Two-year clinical outcomes of standalone gonioscopy-assisted transluminal trabeculotomy in normal-tension glaucoma

S. Liu, Liuzhi Zeng, Zhengfang Wu, Ping Yu et al.
Frontiers in Medicine
Glaucoma and retinal disorders
article

Two-year clinical outcomes of standalone gonioscopy-assisted transluminal trabeculotomy in normal-tension glaucoma

S. Liu, Liuzhi Zeng, Zhengfang Wu, Ping Yu, Xiao Tang
article en

Abstract

Purpose: To evaluate the 2-year efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) for normal-tension glaucoma (NTG). Methods: tests or Wilcoxon signed-rank tests were used as appropriate; a one-eye-per-patient sensitivity analysis was performed. Results: = 9) was consistent. No hypotony, IOP spikes, or serious complications occurred. Events were mild and self-limited (mainly hyphema and aqueous flare). No SLT, needling, or additional glaucoma surgery was required. Conclusion: GATT significantly reduced IOP and medication burden in NTG with a safety profile through 24 months. Larger prospective studies are warranted.

Frontiers in MedicineVol. 13
Chengdu University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 14%
Glaucoma and retinal disorders
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