Effect of Mitochondrial Ca<sup>2+</sup> Uptake on Arrhythmogenesis in Right Ventricular Hypertrophy in Rats and Mice
BACKGROUND: uptake affects ventricular arrhythmias in right ventricular hypertrophy (RVH). METHODS AND RESULTS: wave velocity, the 2',7'-dichlorofluorescein fluorescence slope, and MitoSox Red fluorescence in the MCT-rats. MCU expression increased with the degree of RVH. CONCLUSIONS: uptake, ROS production, and MCU expression.
Authors
- Haruka Sato (ORCID: https://orcid.org/0000-0001-6839-0146)
- Sana Koyama
- Yuka Someya
- Yui Takahashi
- Kazunori Kumasaka
- Kao Takeda
- Tsuyoshi Okumura
- Shiori Akazawa
- Masahito Miura
Institutions
- Tohoku University (JP)
Publication Details
- Journal
- Circulation Journal
- Published
- 2026-04-17
- DOI
- https://doi.org/10.1253/circj.cj-25-0856
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 0.00