Admission NT-proBNP as a Prognostic Biomarker for Ventilator Weaning Failure: Implications for Tracheostomy Timing
: Admission NT-proBNP serves as a powerful biomarker associated with cardiopulmonary vulnerability from the earliest stages of critical illness. Integrating this diagnostic biomarker with interventional strategies like optimal tracheostomy timing has significant prognostic implications. This biomarker-guided approach facilitates personalized risk stratification from ICU admission, potentially optimizing weaning pathways for mechanically ventilated patients.
Authors
- Geun In Lee
- Se Hyun Kwak (ORCID: https://orcid.org/0000-0002-5680-111X)
- Ah Young Leem (ORCID: https://orcid.org/0000-0001-5165-3704)
- Shihwan Chang (ORCID: https://orcid.org/0000-0003-2986-2766)
- Song Yee Kim (ORCID: https://orcid.org/0000-0001-8627-486X)
- Youngmok Park (ORCID: https://orcid.org/0000-0002-5669-1491)
- Young Ae Kang (ORCID: https://orcid.org/0000-0002-7783-5271)
- Moo Suk Park (ORCID: https://orcid.org/0000-0003-0820-7615)
- Hye Young Hong (ORCID: https://orcid.org/0009-0004-4905-4103)
- Young Sam Kim (ORCID: https://orcid.org/0000-0001-9656-8482)
- S J Yong
- Eun Young Kim (ORCID: https://orcid.org/0000-0002-3281-5744)
- Chan Ho Lee (ORCID: https://orcid.org/0000-0003-2065-7379)
- K CHUNG
- MINDONG SUNG
- S H Lee
- Su Hwan Lee
- Ji Ye Jung
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
Publication Details
- Journal
- Biomedicines
- Published
- 2026-04-17
- DOI
- https://doi.org/10.3390/biomedicines14040916
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Korea Health Industry Development Institute
- Yonsei University College of Medicine