Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge

platform enables targeted delivery of biologics to the lung, modulates the lung environment, and improves pathology without inducing systemic immune reactions.

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Publication Details

Journal
Science Immunology
Published
2026-04-17
DOI
https://doi.org/10.1126/sciimmunol.adv7969
Primary Topic
Cancer Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge

Stéphanie Humblet‐Baron, Ntombizodwa Makuyana, Lauren Michiels, Amy Dashwood et al.
Science Immunology
Cancer Research and Treatments
article

Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge

Stéphanie Humblet‐Baron, Ntombizodwa Makuyana, Lauren Michiels, Amy Dashwood, Ekhlas Rahman, Oliver T. Burton, Stéphane M. Guillaume, Joost Wauters, Michelle A. Linterman, Lubna Kouser, Greetje Vande Velde, K. N. Singh, Stéphanie Liénart, Lieve M. J. Naesens, Régis Joulia, Adrian Liston, Laura Seldeslachts, Magda Ali, Arman Ghodsinia, Alvaro R. Hernandez, Marwane Achkir, Laura M. Kops, Fran Naranjo
article en

Abstract

platform enables targeted delivery of biologics to the lung, modulates the lung environment, and improves pathology without inducing systemic immune reactions.

Science ImmunologyVol. 11(118)
Uppsala University (SE), Babraham Institute (GB), MRC Laboratory of Molecular Biology (GB), Malaghan Institute of Medical Research (NZ), University of Cambridge (GB), Imperial College London (GB), KU Leuven (BE)
Wellcome Trust, Fonds Wetenschappelijk Onderzoek, Gates Cambridge Trust, Wallonie-Bruxelles International, Vlaamse regering, H2020 European Research Council
Openalex Percentile: Top 18%
Cancer Research and Treatments
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