Fucoidans as multifunctional marine polysaccharide platforms: From nutritional supplements to advanced drug delivery for cancer therapy

, anti-epidermal growth factor receptor (EGFR)), are discussed for further optimizing performance. Beyond oncology, the review also covers promising applications in renal protection, wound healing, and antimicrobial therapy. Finally, current challenges such as structural heterogeneity and the gap to clinical translation are addressed, with future directions proposed involving standardization, intelligent design, and comprehensive preclinical validation. This review aims to serve as a strategic reference for the rational design and clinical translation of fucoidan-based nanomedicines.

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Publication Details

Journal
International Journal of Pharmaceutics X
Published
2026-04-17
DOI
https://doi.org/10.1016/j.ijpx.2026.100546
Primary Topic
Seaweed-derived Bioactive Compounds
Type
article
Field-Weighted Citation Impact
0.00
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article

Fucoidans as multifunctional marine polysaccharide platforms: From nutritional supplements to advanced drug delivery for cancer therapy

Lin Long, Chuanlong Guo, Jianhua Zang, Gaoyang Lin et al.
International Journal of Pharmaceutics X
Seaweed-derived Bioactive Compounds
article

Fucoidans as multifunctional marine polysaccharide platforms: From nutritional supplements to advanced drug delivery for cancer therapy

Lin Long, Chuanlong Guo, Jianhua Zang, Gaoyang Lin, Yuning Liu, Jun Xiao
article en

Abstract

, anti-epidermal growth factor receptor (EGFR)), are discussed for further optimizing performance. Beyond oncology, the review also covers promising applications in renal protection, wound healing, and antimicrobial therapy. Finally, current challenges such as structural heterogeneity and the gap to clinical translation are addressed, with future directions proposed involving standardization, intelligent design, and comprehensive preclinical validation. This review aims to serve as a strategic reference for the rational design and clinical translation of fucoidan-based nanomedicines.

International Journal of Pharmaceutics XVol. 11
Qingdao University (CN), Qingdao University of Science and Technology (CN), Affiliated Hospital of Qingdao University (CN)
Zero hunger
Openalex Percentile: Top 20%
Seaweed-derived Bioactive Compounds
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