Marked Improvement in Pulmonary Arterial Hypertension in 3 Patients with a History of Amphetamine-like Drug use and Comorbidities

Introduction/background The prognosis of patients with Pulmonary Hypertension (PAH) associated with the intake of anorexigens and amphetamines has not been clearly defined. Published data are suboptimal due to a scarcity of corroborating hemodynamic information. There are reports of worse, the same, and better prognoses compared to patients with idiopathic pulmonary arterial hypertension. Case presentation Our experience with three patients who had PAH, a history of amphetamine-like drug use, and comorbidities is described, and the pertinent literature is summarized. Conclusion Three patients with PAH and a history of amphetamine-like drug use demonstrated markedly improved hemodynamics at follow-up catheterizations.