Reactive Hyperemia: revisiting a key vascular feature of cardiorespiratory fitness.

Although flow-mediated dilation (FMD) is a well-established marker of conduit artery endothelial function, it is not optimally suited to detect endurance exercise training-mediated vascular adaptations in healthy individuals. Herein, we evaluate reactive hyperemia (RH), adding resistance-vessel and microvascular responses, as a physiological feature that more closely reflects the peripheral remodeling and physiological environment associated with cardiorespiratory fitness (CRF). SUMMARY: Reactive hyperemia captures training-related vascular adaptations more effectively than conduit artery dilation in healthy endurance-trained individuals.