CuiT is a Cu importer required for metal homeostasis in Salmonella enterica
Cu homeostasis network, linking Cu import to transcriptional regulation, redox balance, and stress adaptation. Our work provides mechanistic insights into bacterial Cu acquisition and suggests CuiT and associated pathways as potential targets for antimicrobial strategies.
Authors
- José Argüello (ORCID: https://orcid.org/0000-0003-3940-6297)
- Teresita Padilla‐Benavides (ORCID: https://orcid.org/0000-0002-4624-0822)
- Fernando C. Soncini (ORCID: https://orcid.org/0000-0002-8925-7763)
- Karla Díaz-Rodríguez (ORCID: https://orcid.org/0000-0003-2329-7567)
- Susana K. Checa (ORCID: https://orcid.org/0000-0003-1629-2848)
- Pedro Mendes (ORCID: https://orcid.org/0000-0001-6507-9168)
- Lisandro M. Sommer
- Andrea A.E. Mendez (ORCID: https://orcid.org/0009-0004-0013-3994)
Institutions
- Wesleyan University (US)
- Worcester Polytechnic Institute (US)
- University of Connecticut (US)
- National University of Rosario (AR)
- Instituto de Biología Molecular y Celular de Rosario (AR)
- UConn Health (US)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2026-04-17
- DOI
- https://doi.org/10.1016/j.bbrep.2026.102581
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Center for the Humanities, Wesleyan University
- Universidad Nacional de Rosario
- Consejo Nacional de Investigaciones Científicas y Técnicas
- National Institutes of Health