Rational Design of Schiff Base Copper Chelators as Potent Necroptosis Inducers for Anticancer Therapy
. This study presents both an effective optimization strategy for Schiff base copper chelators and a promising anticancer candidate.
Authors
- Cai‐Ping Tan (ORCID: https://orcid.org/0000-0003-3583-8367)
- Qingyuan Hu (ORCID: https://orcid.org/0000-0003-0215-4559)
- Long‐Bo Yu
- Feng Li (ORCID: https://orcid.org/0000-0001-5892-6496)
- Qi‐Xin Guan
- Zhi-Bo Zhu
- Man-Chun Liu
- Shuo-Ting Huang
- Qing Ren
Institutions
- State Key Laboratory of Synthetic Chemistry (CN)
- TCM-Intigrated Cancer Center of Southern Medical University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Medicinal Chemistry
- Published
- 2026-04-17
- DOI
- https://doi.org/10.1021/acs.jmedchem.5c03604
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Fundamental Research Funds for the Central Universities
- Basic and Applied Basic Research Foundation of Guangdong Province