Chemical Composition Analysis of Highland Barley (Hordeum vulgare L.) with Different Modification Methods and Lipid Metabolism Mechanism Analysis of Highland Barley with Microwave Fluidization Modification

related to the PPAR signaling pathway, which played key roles in lipid metabolism. Moreover, qRT-PCR and WB results indicated that HB-1 obviously enhanced ADIPOQ expression level, while it reduced SCD-1, CD36, Fabp4, and SREBP-1c expression levels, suggesting that the alleviation of lipid metabolic dysregulation by HB-1 in hyperlipidemia mice might be mediated via participating in the PPARγ pathway. This study provided essential theoretical insights for the development and utilization of HB.

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Publication Details

Journal
Foods
Published
2026-04-17
DOI
https://doi.org/10.3390/foods15081396
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
Field-Weighted Citation Impact
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article

Chemical Composition Analysis of Highland Barley (Hordeum vulgare L.) with Different Modification Methods and Lipid Metabolism Mechanism Analysis of Highland Barley with Microwave Fluidization Modification

Pengxiao Chen, Kevin Shyong Wei Tan, Xiang Li
Foods
Metabolomics and Mass Spectrometry Studies
article

Chemical Composition Analysis of Highland Barley (Hordeum vulgare L.) with Different Modification Methods and Lipid Metabolism Mechanism Analysis of Highland Barley with Microwave Fluidization Modification

Pengxiao Chen, Kevin Shyong Wei Tan, Xiang Li
article en

Abstract

related to the PPAR signaling pathway, which played key roles in lipid metabolism. Moreover, qRT-PCR and WB results indicated that HB-1 obviously enhanced ADIPOQ expression level, while it reduced SCD-1, CD36, Fabp4, and SREBP-1c expression levels, suggesting that the alleviation of lipid metabolic dysregulation by HB-1 in hyperlipidemia mice might be mediated via participating in the PPARγ pathway. This study provided essential theoretical insights for the development and utilization of HB.

FoodsVol. 15(8)
National University of Singapore (SG), Henan University of Technology (CN)
Openalex Percentile: Top 21%
Metabolomics and Mass Spectrometry Studies
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